The transformation of urban landscapes, driven by socio-economic dynamics, both reflects and drives a country’s development. The accessibility, efficiency and quality of environmental and social infrastructures play a key role in their ability to meet the needs of residents and improve their well-being. Optimised management of these infrastructures also helps to strengthen the resilience and sustainability of urban and regional areas. This study, based on the analysis of Tunisian households’ preferences through the estimation of a hedonic model integrating spatial interrelations, explores the local environmental factors that influence residential choices. It is based on a geo-referenced micro-database of 613 dwellings and focuses on amenities and disamenities in three governorates of the Tunis metropolitan area. The results revealed that the Durbin Spatial Model (DSM), which incorporates spatial diffusion and spillover effects, was the most suitable for analysing housing applicants’ decisions. Proximity to education was identified as a major priority in residential preferences, surpassing the attractiveness of proximity to the sea. These findings highlight the importance of essential services for homeowners, while the influence of environmental factors appears to vary according to the socio-economic characteristics of households. On the other hand, factors such as high levels of unemployment and poverty negatively affect property values in certain neighbourhoods in the Tunis metropolitan area. These results, in the context of rapid urbanisation and budgetary constraints as in Tunisia, highlight the urgent need to implement targeted urban development policies that reduce socio-economic disparities while improving access to priority infrastructure and services.