The Seine Axis is the first European basin for the production of drugs. More than half of this production is exported. It is organized by the main international leaders which have been implanted in the region for several decades with an international development policy. Therefore, under the dynamic of globalization, this territory has had to adapt in order to be or to remain attractive, so as to increase the competitiveness of the pharmaceutical sector. This is being achieved in particular by developing two dedicated business parks in Normandy. Furthermore, in the context of global geoeconomic uncertainty, France has decided to support the sector by creating a new specific territory : the Seine Axis, as well as providing useful tools to facilitate the linkage between the territory and its companies. One of the levers for action relies on the process of digital transformation, and  particularly on blockchain technology which influences the generative processes of flows, and not only merchandise flows. The use of blockchain technology with generative processes of drug flows means assessing action possibilities in the field of regional development in the pharmaceutical industry, or in their logistic organizations. Study is therefore needed specifically on the policies of geographical location of the industries and logistics platforms in this field. This research concerning the various forms of numerical consequences on the future of supply chain, with the blockchain, in the pharmaceutical sector, implies numerous innovations, within a framework of an active approach, by public authorities to the logistics domain of industry and retail.